Tamzen

Tamzen

213.00 850.00

Tamzen(Tamsulin 0.4mg Tablet) is an alpha-adrenergic antagonist used to treat the symptoms of benign prostatic hyperplasia (enlarged prostate), bladder outlet obstruction and kidney stones. It is used by men to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia-BPH). It does not shrink the prostate, but it works by relaxing the muscles in the prostate and the bladder. This helps to relieve symptoms of BPH such as difficulty in beginning the flow of urine, weak stream, and the need to urinate often or urgently (including during the middle of the night).It helps to relieve symptoms like difficulty in passing urine.

Category:

Composition: Tamsulosin 0.4 mg Tablet

Tamzen(Tamsulin 0.4mg Tablet) is an alpha-adrenergic antagonist used to treat the symptoms of benign prostatic hyperplasia (enlarged prostate), bladder outlet obstruction and kidney stones. It is used by men to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia-BPH). It does not shrink the prostate, but it works by relaxing the muscles in the prostate and the bladder. This helps to relieve symptoms of BPH such as difficulty in beginning the flow of urine, weak stream, and the need to urinate often or urgently (including during the middle of the night).It helps to relieve symptoms like difficulty in passing urine.

Tamsulosin belongs to a class of drugs known as alpha blockers.

Do not use this medication to treat high blood pressure.

Indications

Lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH).

Side Effects

Tamzen may cause serious side effects including:

  • lightheadedness and
  • an erection that lasts over 4 or is painful

Get medical help right away, if you have any of the symptoms listed above.

The most common side effects of Tamzen include:

  • abnormal ejaculation,
  • decreased amount of semen,
  • dizziness,
  • drowsiness,
  • weakness,
  • runny nose,
  • cough,
  • back pain,
  • chest pain,
  • nausea,
  • diarrhea,
  • tooth problems,
  • blurred vision,
  • sleep problems (insomnia), and
  • decreased interest in sex

Tell the doctor if you have any side effect that bothers you or that does not go away.

Contraindications

Tamsulosin Hydrochloride Capsules are contraindicated in patients known to be hypersensitive to tamsulosin hydrochloride or any component of Tamsulosin Hydrochloride Capsules.

  • Hypersensitivity to the active substance including drug-induced angioedema
  • History of orthostatic hypotension.
  • Severe hepatic insufficiency.
  • Micturition syncope history

The following adverse reactions have been identified during post-approval use of Tamsulosin Hydrochloride Capsules. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Decisions to include these reactions in labelling are typically based on one or more of the following factors: (1) seriousness of the reaction, (2) frequency of reporting, or (3) strength of causal connection to Tamsulosin Hydrochloride Capsules.

Allergic-type reactions such as skin rash, urticaria, pruritus, angioedema, and respiratory symptoms have been reported with positive rechallenge in some cases. Priapism has been reported rarely. Infrequent reports of dyspnoea, palpitations, hypotension, atrial fibrillation, arrhythmia, tachycardia, skin desquamation including reports of Stevens-Johnson syndrome, erythema multiforme, dermatitis exfoliative,constipation, vomiting, dry mouth, visual impairment, and epistaxis have been received during the post marketing period.

During cataract and glaucoma surgery, a variant of small pupil syndrome known as Intraoperative Floppy Iris Syndrome (IFIS) has been reported in association with alpha 1 blocker therapy.

Pharmacodynamics

Tamsulosin is an alpha adrenoceptor blocker with specificity for the alpha-1A and alpha-1D subtypes, which are more common in the prostate and submaxillary tissue. The final subtype, alpha-1B, are most common in the aorta and spleen. Tamsulosin binds to alpha-1A receptors 3.9-38 times more selectively than alpha-1B and 3-20 times more selectively than alpha-1D. This selectivity allows for a significant effect on urinary flow with a reduced incidence of adverse reactions like orthostatic hypotension.

Mechanism of Action

Tamsulosin is a blocker of alpha-1A and alpha-1D adrenoceptors.Label, About 70% of the alpha-1 adrenoceptors in the prostate are of the alpha-1A subtype.Label By blocking these adrenoceptors, smooth muscle in the prostate is relaxed and urinary flow is improved.Label The blocking of alpha-1D adrenoceptors relaxes the detrusor muscles of the bladder which prevents storage symptoms. The specificity of tamsulosin focuses the effects to the target area while minimizing effects in other areas.

Storage

Store below 25 °Caway from moisture and Sunlight.

Tamzen Contains

Tamsulosin 0.4 mg