Balofloxacin is used in the treatment of bacterial infections. It is used to treat a variety of bacterial infections of the urinary tract and lungs. It is also used in infections of urinary tract, tonsils, sinus, nose, throat, female genital organ, skin and soft tissues and lungs (pneumonia).
Balofloxacin is an antibiotic. It works by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents the bacterial cells from dividing and repairing, thereby killing them.
It should be avoided in patients who are allergic to other fluoroquinolones. Use with caution in the elderly population as it increases the risk of tendinitis and tendon rupture.Take Balofloxacin with or without food. Do not take in larger amounts than advised.
Indications
Urinary Tract Infection
BALOZEN – 100 Tablet is used in the treatment of urinary tract infections caused by E. coli, Pseudomonas aeruginosa, Enterococci and Klebsiella pneumoniae.
Pneumonia
BALOZEN – 100 Tablet is used in the treatment of pneumonia which is a common type of lung infection caused by Streptococcus pneumoniae and Haemophilus influenzae
Contraindications
Allergy
Tendinitis or Tendon Rupture
Myasthenia Gravis
Side Effects
Major & minor side effects for BALOZEN – 100 Tablet
Nausea
Heartburn
Dizziness
Fever
Indigestion
Increased thirst
Abdominal pain
Skin rash
Headache
Loss of appetite
Pharmacodynamics
Balofloxacin exerts bactericidal property by inhibition of bacterial DNA gyrase. The enzyme is important for synthesis of bacterial DNA.
Mechanism of Action
The bactericidal action of Balofloxacin results from interference with the enzyme DNA gyrase which is needed for the synthesis of bacterial DNA. Balofloxacin is efficacious against Gram-negative bacteria. It also has enhanced activity against Gram positive bacteria, including MRSA and Streptococcus pneumoniae.
